Jessica Biel is the second wife of Mr. Peanutbutter. She is based on the real-life American actress of the same name.
In the episode The BoJack Horseman Show, set in 2007, Mr. Peanutbutter is noticeably jealous of Jessica's friendship with Justin Timberlake and she hints that she would want to marry him - in real life, Biel and Timberlake began dating in 2007 and would go on to marry in 2012.